Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is a major cause of drug attrition. Testing drugs on human liver models is essential to mitigate the risk of clinical DILI since animal studies do not always suffice due to species-specific differences in liver pathways. While primary human hepatocytes (PHHs) can be...

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Detalles Bibliográficos
Autores principales: Lin, Christine, Khetani, Salman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048025/
https://www.ncbi.nlm.nih.gov/pubmed/27725933
http://dx.doi.org/10.1155/2016/1829148

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