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Survival Motor Neuron (SMN) protein is required for normal mouse liver development

Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of, cell-ubiquitous, SMN protein is associated with a range of systemic pathologies reported in severe patients. Despite high levels of SMN protein in normal liver, there is n...

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Detalles Bibliográficos
Autores principales:	Szunyogova, Eva, Zhou, Haiyan, Maxwell, Gillian K., Powis, Rachael A., Francesco, Muntoni, Gillingwater, Thomas H., Parson, Simon H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048144/ https://www.ncbi.nlm.nih.gov/pubmed/27698380 http://dx.doi.org/10.1038/srep34635

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