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Outer membrane vesicles from flagellin-deficient Salmonella enterica serovar Typhimurium induce cross-reactive immunity and provide cross-protection against heterologous Salmonella challenge

Outer membrane vesicles (OMVs) isolated from Salmonella Typhimurium are potentially useful for developing subunit vaccines because of high immunogenicity and protective efficacy. However, flagella might remain in OMV pellets following OMV purification, resulting in non-essential immune responses and...

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Detalles Bibliográficos
Autores principales: Liu, Qiong, Liu, Qing, Yi, Jie, Liang, Kang, Hu, Bo, Zhang, Xiangmin, Curtiss, Roy, Kong, Qingke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048178/
https://www.ncbi.nlm.nih.gov/pubmed/27698383
http://dx.doi.org/10.1038/srep34776