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Outer membrane vesicles from flagellin-deficient Salmonella enterica serovar Typhimurium induce cross-reactive immunity and provide cross-protection against heterologous Salmonella challenge
Outer membrane vesicles (OMVs) isolated from Salmonella Typhimurium are potentially useful for developing subunit vaccines because of high immunogenicity and protective efficacy. However, flagella might remain in OMV pellets following OMV purification, resulting in non-essential immune responses and...
Autores principales: | Liu, Qiong, Liu, Qing, Yi, Jie, Liang, Kang, Hu, Bo, Zhang, Xiangmin, Curtiss, Roy, Kong, Qingke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048178/ https://www.ncbi.nlm.nih.gov/pubmed/27698383 http://dx.doi.org/10.1038/srep34776 |
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