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Histone acetylation dependent energy landscapes in tri-nucleosome revealed by residue-resolved molecular simulations
Histone tail acetylation is a key epigenetic marker that tends to open chromatin folding and activate transcription. Despite intensive studies, precise roles of individual lysine acetylation in chromatin folding have only been poorly understood. Here, we revealed structural dynamics of tri-nucleosom...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048180/ https://www.ncbi.nlm.nih.gov/pubmed/27698366 http://dx.doi.org/10.1038/srep34441 |