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Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV
Reduced promoter IV-driven expression of brain-derived neurotrophic factor (BDNF) is implicated in stress and major depression. We previously reported that defective promoter IV (KIV) caused depression-like behavior in young adult mice, which was reversed more effectively by enriched environment tre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048201/ https://www.ncbi.nlm.nih.gov/pubmed/27648918 http://dx.doi.org/10.1038/tp.2016.160 |