Cargando…

Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV

Reduced promoter IV-driven expression of brain-derived neurotrophic factor (BDNF) is implicated in stress and major depression. We previously reported that defective promoter IV (KIV) caused depression-like behavior in young adult mice, which was reversed more effectively by enriched environment tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Jha, S, Dong, B E, Xue, Y, Delotterie, D F, Vail, M G, Sakata, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048201/
https://www.ncbi.nlm.nih.gov/pubmed/27648918
http://dx.doi.org/10.1038/tp.2016.160