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Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid

Autism spectrum disorders (ASD) are characterized by altered sociability, compromised communication and stereotyped/repetitive behaviors, for which no specific treatments are currently available. Prenatal exposure to valproic acid (VPA) is a known, although still underestimated, environmental risk f...

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Detalles Bibliográficos
Autores principales: Servadio, M, Melancia, F, Manduca, A, di Masi, A, Schiavi, S, Cartocci, V, Pallottini, V, Campolongo, P, Ascenzi, P, Trezza, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048215/
https://www.ncbi.nlm.nih.gov/pubmed/27676443
http://dx.doi.org/10.1038/tp.2016.182