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NSUN3 and ABH1 modify the wobble position of mt‐tRNA (Met) to expand codon recognition in mitochondrial translation

Mitochondrial gene expression uses a non‐universal genetic code in mammals. Besides reading the conventional AUG codon, mitochondrial (mt‐)tRNA(M) (et) mediates incorporation of methionine on AUA and AUU codons during translation initiation and on AUA codons during elongation. We show that the RNA m...

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Detalles Bibliográficos
Autores principales: Haag, Sara, Sloan, Katherine E, Ranjan, Namit, Warda, Ahmed S, Kretschmer, Jens, Blessing, Charlotte, Hübner, Benedikt, Seikowski, Jan, Dennerlein, Sven, Rehling, Peter, Rodnina, Marina V, Höbartner, Claudia, Bohnsack, Markus T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048346/
https://www.ncbi.nlm.nih.gov/pubmed/27497299
http://dx.doi.org/10.15252/embj.201694885