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NSUN3 and ABH1 modify the wobble position of mt‐tRNA (Met) to expand codon recognition in mitochondrial translation
Mitochondrial gene expression uses a non‐universal genetic code in mammals. Besides reading the conventional AUG codon, mitochondrial (mt‐)tRNA(M) (et) mediates incorporation of methionine on AUA and AUU codons during translation initiation and on AUA codons during elongation. We show that the RNA m...
Autores principales: | Haag, Sara, Sloan, Katherine E, Ranjan, Namit, Warda, Ahmed S, Kretschmer, Jens, Blessing, Charlotte, Hübner, Benedikt, Seikowski, Jan, Dennerlein, Sven, Rehling, Peter, Rodnina, Marina V, Höbartner, Claudia, Bohnsack, Markus T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048346/ https://www.ncbi.nlm.nih.gov/pubmed/27497299 http://dx.doi.org/10.15252/embj.201694885 |
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