Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)

The oxidant and antioxidant equilibrium is known to play an important role in equine medicine and equine exercise physiology. There are abundant findings in this field; however, not many studies have been conducted for reference ranges of oxidative stress biomarkers in horses. This study was conduct...

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Autores principales: KUSANO, Kanichi, YAMAZAKI, Masahiko, KIUCHI, Masataka, KANEKO, Kouki, KOYAMA, Katsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Equine Science 2016
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048360/
https://www.ncbi.nlm.nih.gov/pubmed/27703408
http://dx.doi.org/10.1294/jes.27.125
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author KUSANO, Kanichi
YAMAZAKI, Masahiko
KIUCHI, Masataka
KANEKO, Kouki
KOYAMA, Katsuhiro
author_facet KUSANO, Kanichi
YAMAZAKI, Masahiko
KIUCHI, Masataka
KANEKO, Kouki
KOYAMA, Katsuhiro
author_sort KUSANO, Kanichi
collection PubMed
description The oxidant and antioxidant equilibrium is known to play an important role in equine medicine and equine exercise physiology. There are abundant findings in this field; however, not many studies have been conducted for reference ranges of oxidative stress biomarkers in horses. This study was conducted to determine the reference values of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) using blood samples from 372 (191 males, 181 females) Thoroughbred racehorse aged 2 to 5 (3.43 ± 1.10 (mean ± SD)) years old. There were obvious gender differences in oxidative biomarkers, and growth/age-related changes were observed especially in females. Gender and age must be considered when interpreting obtained oxidative stress biomarkers for diagnosis of disease or fitness alterations in Thoroughbred racehorses.
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spelling pubmed-50483602016-10-04 Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old) KUSANO, Kanichi YAMAZAKI, Masahiko KIUCHI, Masataka KANEKO, Kouki KOYAMA, Katsuhiro J Equine Sci Note The oxidant and antioxidant equilibrium is known to play an important role in equine medicine and equine exercise physiology. There are abundant findings in this field; however, not many studies have been conducted for reference ranges of oxidative stress biomarkers in horses. This study was conducted to determine the reference values of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) using blood samples from 372 (191 males, 181 females) Thoroughbred racehorse aged 2 to 5 (3.43 ± 1.10 (mean ± SD)) years old. There were obvious gender differences in oxidative biomarkers, and growth/age-related changes were observed especially in females. Gender and age must be considered when interpreting obtained oxidative stress biomarkers for diagnosis of disease or fitness alterations in Thoroughbred racehorses. The Japanese Society of Equine Science 2016-09-30 2016 /pmc/articles/PMC5048360/ /pubmed/27703408 http://dx.doi.org/10.1294/jes.27.125 Text en 2016 The Japanese Society of Equine Science http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Note
KUSANO, Kanichi
YAMAZAKI, Masahiko
KIUCHI, Masataka
KANEKO, Kouki
KOYAMA, Katsuhiro
Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title_full Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title_fullStr Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title_full_unstemmed Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title_short Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old)
title_sort reference range of blood biomarkers for oxidative stress in thoroughbred racehorses (2–5 years old)
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048360/
https://www.ncbi.nlm.nih.gov/pubmed/27703408
http://dx.doi.org/10.1294/jes.27.125
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