Cargando…
Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters
Hypoxia‐inducible factor (HIF) directs an extensive transcriptional cascade that transduces numerous adaptive responses to hypoxia. Pan‐genomic analyses, using chromatin immunoprecipitation and transcript profiling, have revealed large numbers of HIF‐binding sites that are generally associated with...
Autores principales: | Platt, James L, Salama, Rafik, Smythies, James, Choudhry, Hani, Davies, James OJ, Hughes, Jim R, Ratcliffe, Peter J, Mole, David R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048371/ https://www.ncbi.nlm.nih.gov/pubmed/27506891 http://dx.doi.org/10.15252/embr.201642198 |
Ejemplares similares
-
Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin
por: Smythies, James A, et al.
Publicado: (2018) -
Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway
por: Grampp, Steffen, et al.
Publicado: (2017) -
Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
por: Choudhry, Hani, et al.
Publicado: (2014) -
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
por: Schmid, Virginia, et al.
Publicado: (2019) -
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma
por: Lafleur, Véronique N, et al.
Publicado: (2023)