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Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathies

We have developed a novel real‐time quaking‐induced conversion RT‐QuIC‐based assay to detect alpha‐synuclein aggregation in brain and cerebrospinal fluid from dementia with Lewy bodies and Parkinson's disease patients. This assay can detect alpha‐synuclein aggregation in Dementia with Lewy bodi...

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Detalles Bibliográficos
Autores principales: Fairfoul, Graham, McGuire, Lynne I., Pal, Suvankar, Ironside, James W., Neumann, Juliane, Christie, Sharon, Joachim, Catherine, Esiri, Margaret, Evetts, Samuel G., Rolinski, Michal, Baig, Fahd, Ruffmann, Claudio, Wade‐Martins, Richard, Hu, Michele T. M., Parkkinen, Laura, Green, Alison J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048391/
https://www.ncbi.nlm.nih.gov/pubmed/27752516
http://dx.doi.org/10.1002/acn3.338