Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks

Measuring substrate and/or product concentration can create a major bottleneck for synthetic and biosynthetic processes. Here we report the development and substrate screening of a whole cell biosensor to detect biomass-derived aromatic chemical building blocks, supporting the use of sustainable fee...

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Detalles Bibliográficos
Autores principales: Machado, Leopoldo F. M., Dixon, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048394/
https://www.ncbi.nlm.nih.gov/pubmed/27722239
http://dx.doi.org/10.1039/c6cc04559f
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author Machado, Leopoldo F. M.
Dixon, Neil
author_facet Machado, Leopoldo F. M.
Dixon, Neil
author_sort Machado, Leopoldo F. M.
collection PubMed
description Measuring substrate and/or product concentration can create a major bottleneck for synthetic and biosynthetic processes. Here we report the development and substrate screening of a whole cell biosensor to detect biomass-derived aromatic chemical building blocks, supporting the use of sustainable feedstocks in the bulk and fine chemical industries.
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spelling pubmed-50483942016-10-12 Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks Machado, Leopoldo F. M. Dixon, Neil Chem Commun (Camb) Chemistry Measuring substrate and/or product concentration can create a major bottleneck for synthetic and biosynthetic processes. Here we report the development and substrate screening of a whole cell biosensor to detect biomass-derived aromatic chemical building blocks, supporting the use of sustainable feedstocks in the bulk and fine chemical industries. Royal Society of Chemistry 2016-10-15 2016-08-25 /pmc/articles/PMC5048394/ /pubmed/27722239 http://dx.doi.org/10.1039/c6cc04559f Text en This journal is © The Royal Society of Chemistry 2016 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Machado, Leopoldo F. M.
Dixon, Neil
Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title_full Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title_fullStr Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title_full_unstemmed Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title_short Development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
title_sort development and substrate specificity screening of an in vivo biosensor for the detection of biomass derived aromatic chemical building blocks
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048394/
https://www.ncbi.nlm.nih.gov/pubmed/27722239
http://dx.doi.org/10.1039/c6cc04559f
work_keys_str_mv AT machadoleopoldofm developmentandsubstratespecificityscreeningofaninvivobiosensorforthedetectionofbiomassderivedaromaticchemicalbuildingblocks
AT dixonneil developmentandsubstratespecificityscreeningofaninvivobiosensorforthedetectionofbiomassderivedaromaticchemicalbuildingblocks

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