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TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress
BACKGROUND: Staphylococcus aureus is the principle causative pathogen of osteomyelitis and implant-associated bone infections. It is able to invade and to proliferate inside osteoblasts thus avoiding antibiotic therapy and the host immune system. Therefore, development of alternative approaches to s...
Autores principales: | Mohamed, Walid, Domann, Eugen, Chakraborty, Trinad, Mannala, Gopala, Lips, Katrin S., Heiss, Christian, Schnettler, Reinhard, Alt, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048406/ https://www.ncbi.nlm.nih.gov/pubmed/27716055 http://dx.doi.org/10.1186/s12866-016-0855-8 |
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