A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system

The ubiquitin-proteasome system (UPS) is a selective protein degradation system that plays a critical role in many essential biological processes by regulating the existence of various cellular proteins. The target proteins of UPS are recognized and tagged with polyubiquitin chains by E3 ubiquitin l...

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Detalles Bibliográficos
Autores principales: Kuchimaru, Takahiro, Suka, Tomoya, Hirota, Keisuke, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048432/
https://www.ncbi.nlm.nih.gov/pubmed/27698477
http://dx.doi.org/10.1038/srep34311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048432/
https://www.ncbi.nlm.nih.gov/pubmed/27698477
http://dx.doi.org/10.1038/srep34311

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