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SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES

Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia...

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Autores principales: CUNHA, Francisco Afrânio, MAIA, Kamila Rocha, MALLMAN, Eduardo José Jucá, CUNHA, Maria da Conceição dos Santos Oliveira, MACIEL, Antonio Auberson Martins, de SOUZA, Ieda Pereira, MENEZES, Everardo Albuquerque, FECHINE, Pierre Basílio Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048644/
https://www.ncbi.nlm.nih.gov/pubmed/27680178
http://dx.doi.org/10.1590/S1678-9946201658073
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author CUNHA, Francisco Afrânio
MAIA, Kamila Rocha
MALLMAN, Eduardo José Jucá
CUNHA, Maria da Conceição dos Santos Oliveira
MACIEL, Antonio Auberson Martins
de SOUZA, Ieda Pereira
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author_facet CUNHA, Francisco Afrânio
MAIA, Kamila Rocha
MALLMAN, Eduardo José Jucá
CUNHA, Maria da Conceição dos Santos Oliveira
MACIEL, Antonio Auberson Martins
de SOUZA, Ieda Pereira
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author_sort CUNHA, Francisco Afrânio
collection PubMed
description Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections.
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spelling pubmed-50486442016-10-17 SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES CUNHA, Francisco Afrânio MAIA, Kamila Rocha MALLMAN, Eduardo José Jucá CUNHA, Maria da Conceição dos Santos Oliveira MACIEL, Antonio Auberson Martins de SOUZA, Ieda Pereira MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida Rev Inst Med Trop Sao Paulo Brief Communication Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections. Instituto de Medicina Tropical 2016-09-22 /pmc/articles/PMC5048644/ /pubmed/27680178 http://dx.doi.org/10.1590/S1678-9946201658073 Text en http://creativecommons.org/licenses/by-nc/4.0/ Este é um artigo publicado em acesso aberto sob uma licença Creative Commons
spellingShingle Brief Communication
CUNHA, Francisco Afrânio
MAIA, Kamila Rocha
MALLMAN, Eduardo José Jucá
CUNHA, Maria da Conceição dos Santos Oliveira
MACIEL, Antonio Auberson Martins
de SOUZA, Ieda Pereira
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title_full SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title_fullStr SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title_full_unstemmed SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title_short SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
title_sort silver nanoparticles-disk diffusion test against escherichia coli isolates
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048644/
https://www.ncbi.nlm.nih.gov/pubmed/27680178
http://dx.doi.org/10.1590/S1678-9946201658073
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