Cargando…
SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048644/ https://www.ncbi.nlm.nih.gov/pubmed/27680178 http://dx.doi.org/10.1590/S1678-9946201658073 |
_version_ | 1782457609303883776 |
---|---|
author | CUNHA, Francisco Afrânio MAIA, Kamila Rocha MALLMAN, Eduardo José Jucá CUNHA, Maria da Conceição dos Santos Oliveira MACIEL, Antonio Auberson Martins de SOUZA, Ieda Pereira MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida |
author_facet | CUNHA, Francisco Afrânio MAIA, Kamila Rocha MALLMAN, Eduardo José Jucá CUNHA, Maria da Conceição dos Santos Oliveira MACIEL, Antonio Auberson Martins de SOUZA, Ieda Pereira MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida |
author_sort | CUNHA, Francisco Afrânio |
collection | PubMed |
description | Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections. |
format | Online Article Text |
id | pubmed-5048644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Instituto de Medicina Tropical |
record_format | MEDLINE/PubMed |
spelling | pubmed-50486442016-10-17 SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES CUNHA, Francisco Afrânio MAIA, Kamila Rocha MALLMAN, Eduardo José Jucá CUNHA, Maria da Conceição dos Santos Oliveira MACIEL, Antonio Auberson Martins de SOUZA, Ieda Pereira MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida Rev Inst Med Trop Sao Paulo Brief Communication Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections. Instituto de Medicina Tropical 2016-09-22 /pmc/articles/PMC5048644/ /pubmed/27680178 http://dx.doi.org/10.1590/S1678-9946201658073 Text en http://creativecommons.org/licenses/by-nc/4.0/ Este é um artigo publicado em acesso aberto sob uma licença Creative Commons |
spellingShingle | Brief Communication CUNHA, Francisco Afrânio MAIA, Kamila Rocha MALLMAN, Eduardo José Jucá CUNHA, Maria da Conceição dos Santos Oliveira MACIEL, Antonio Auberson Martins de SOUZA, Ieda Pereira MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title | SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title_full | SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title_fullStr | SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title_full_unstemmed | SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title_short | SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES |
title_sort | silver nanoparticles-disk diffusion test against escherichia coli isolates |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048644/ https://www.ncbi.nlm.nih.gov/pubmed/27680178 http://dx.doi.org/10.1590/S1678-9946201658073 |
work_keys_str_mv | AT cunhafranciscoafranio silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT maiakamilarocha silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT mallmaneduardojosejuca silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT cunhamariadaconceicaodossantosoliveira silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT macielantonioaubersonmartins silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT desouzaiedapereira silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT menezeseverardoalbuquerque silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates AT fechinepierrebasilioalmeida silvernanoparticlesdiskdiffusiontestagainstescherichiacoliisolates |