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Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO)
There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering bot...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hellenic Society of Gastroenterology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049546/ https://www.ncbi.nlm.nih.gov/pubmed/27708505 http://dx.doi.org/10.20524/aog.2016.0050 |
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author | Dervenis, Christos Xynos, Evaghelos Sotiropoulos, George Gouvas, Nikolaos Boukovinas, Ioannis Agalianos, Christos Androulakis, Nikolaos Athanasiadis, Athanasios Christodoulou, Christos Chrysou, Evangelia Emmanouilidis, Christos Georgiou, Panagiotis Karachaliou, Niki Katopodi, Ourania Kountourakis, Panteleimon Kyriazanos, Ioannis Makatsoris, Thomas Papakostas, Pavlos Papamichael, Demetris Pechlivanides, George Pentheroudakis, Georgios Pilpilidis, Ioannis Sgouros, Joseph Tekkis, Paris Triantopoulou, Charina Tzardi, Maria Vassiliou, Vassilis Vini, Louiza Xynogalos, Spyridon Ziras, Nikolaos Souglakos, John |
author_facet | Dervenis, Christos Xynos, Evaghelos Sotiropoulos, George Gouvas, Nikolaos Boukovinas, Ioannis Agalianos, Christos Androulakis, Nikolaos Athanasiadis, Athanasios Christodoulou, Christos Chrysou, Evangelia Emmanouilidis, Christos Georgiou, Panagiotis Karachaliou, Niki Katopodi, Ourania Kountourakis, Panteleimon Kyriazanos, Ioannis Makatsoris, Thomas Papakostas, Pavlos Papamichael, Demetris Pechlivanides, George Pentheroudakis, Georgios Pilpilidis, Ioannis Sgouros, Joseph Tekkis, Paris Triantopoulou, Charina Tzardi, Maria Vassiliou, Vassilis Vini, Louiza Xynogalos, Spyridon Ziras, Nikolaos Souglakos, John |
author_sort | Dervenis, Christos |
collection | PubMed |
description | There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering both special characteristics of our Healthcare System and international guidelines. Following discussion and online communication among the members of an executive team chosen by the Hellenic Society of Medical Oncology (HeSMO), a consensus for metastastic CRC disease was developed. Statements were subjected to the Delphi methodology on two voting rounds by invited multidisciplinary international experts on CRC. Statements reaching level of agreement by ≥80% were considered as having achieved large consensus, whereas statements reaching 60-80% moderate consensus. One hundred and nine statements were developed. Ninety experts voted for those statements. The median rate of abstain per statement was 18.5% (range: 0-54%). In the end of the process, all statements achieved a large consensus. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized. R0 resection is the only intervention that may offer substantial improvement in the oncological outcomes. |
format | Online Article Text |
id | pubmed-5049546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hellenic Society of Gastroenterology |
record_format | MEDLINE/PubMed |
spelling | pubmed-50495462016-10-05 Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) Dervenis, Christos Xynos, Evaghelos Sotiropoulos, George Gouvas, Nikolaos Boukovinas, Ioannis Agalianos, Christos Androulakis, Nikolaos Athanasiadis, Athanasios Christodoulou, Christos Chrysou, Evangelia Emmanouilidis, Christos Georgiou, Panagiotis Karachaliou, Niki Katopodi, Ourania Kountourakis, Panteleimon Kyriazanos, Ioannis Makatsoris, Thomas Papakostas, Pavlos Papamichael, Demetris Pechlivanides, George Pentheroudakis, Georgios Pilpilidis, Ioannis Sgouros, Joseph Tekkis, Paris Triantopoulou, Charina Tzardi, Maria Vassiliou, Vassilis Vini, Louiza Xynogalos, Spyridon Ziras, Nikolaos Souglakos, John Ann Gastroenterol Special Article There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering both special characteristics of our Healthcare System and international guidelines. Following discussion and online communication among the members of an executive team chosen by the Hellenic Society of Medical Oncology (HeSMO), a consensus for metastastic CRC disease was developed. Statements were subjected to the Delphi methodology on two voting rounds by invited multidisciplinary international experts on CRC. Statements reaching level of agreement by ≥80% were considered as having achieved large consensus, whereas statements reaching 60-80% moderate consensus. One hundred and nine statements were developed. Ninety experts voted for those statements. The median rate of abstain per statement was 18.5% (range: 0-54%). In the end of the process, all statements achieved a large consensus. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized. R0 resection is the only intervention that may offer substantial improvement in the oncological outcomes. Hellenic Society of Gastroenterology 2016 2016-06-03 /pmc/articles/PMC5049546/ /pubmed/27708505 http://dx.doi.org/10.20524/aog.2016.0050 Text en Copyright: © Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Article Dervenis, Christos Xynos, Evaghelos Sotiropoulos, George Gouvas, Nikolaos Boukovinas, Ioannis Agalianos, Christos Androulakis, Nikolaos Athanasiadis, Athanasios Christodoulou, Christos Chrysou, Evangelia Emmanouilidis, Christos Georgiou, Panagiotis Karachaliou, Niki Katopodi, Ourania Kountourakis, Panteleimon Kyriazanos, Ioannis Makatsoris, Thomas Papakostas, Pavlos Papamichael, Demetris Pechlivanides, George Pentheroudakis, Georgios Pilpilidis, Ioannis Sgouros, Joseph Tekkis, Paris Triantopoulou, Charina Tzardi, Maria Vassiliou, Vassilis Vini, Louiza Xynogalos, Spyridon Ziras, Nikolaos Souglakos, John Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title | Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title_full | Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title_fullStr | Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title_full_unstemmed | Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title_short | Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) |
title_sort | clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the hellenic society of medical oncologists (hesmo) |
topic | Special Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049546/ https://www.ncbi.nlm.nih.gov/pubmed/27708505 http://dx.doi.org/10.20524/aog.2016.0050 |
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