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Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

BACKGROUND: The asthma gene PCDH1 encodes Protocadherin-1, a putative adhesion molecule of unknown function expressed in the airway epithelium. Here, we characterize the localization, differential expression, homotypic adhesion specificity and function of PCDH1 in airway epithelial cells in asthma....

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Detalles Bibliográficos
Autores principales: Faura Tellez, Grissel, Willemse, Brigitte W. M., Brouwer, Uilke, Nijboer-Brinksma, Susan, Vandepoele, Karl, Noordhoek, Jacobien A., Heijink, Irene, de Vries, Maaike, Smithers, Natalie P., Postma, Dirkje S., Timens, Wim, Wiffen, Laura, van Roy, Frans, Holloway, John W., Lackie, Peter M., Nawijn, Martijn C., Koppelman, Gerard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049773/
https://www.ncbi.nlm.nih.gov/pubmed/27701444
http://dx.doi.org/10.1371/journal.pone.0163967