Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

Activation of pro-inflammatory and pro-angiogenic pathways in the retina and the bone marrow contributes to pathogenesis of diabetic retinopathy. We identified miR-15a as key regulator of both pro-inflammatory and pro-angiogenic pathways through direct binding and inhibition of the central enzyme in...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Navitskaya, Svetlana, Chakravarthy, Harshini, Huang, Chao, Kady, Nermin, Lydic, Todd A., Chen, Y. Eugene, Yin, Ke-Jie, Powell, Folami Lamoke, Martin, Pamela M., Grant, Maria B., Busik, Julia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049929/
https://www.ncbi.nlm.nih.gov/pubmed/27531575
http://dx.doi.org/10.1016/j.ebiom.2016.08.013

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