Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice

BACKGROUND: Transfusion of blood at the limits of approved storage time is associated with lower red blood cell (RBC) post-transfusion recovery and hemolysis, which increases plasma cell-free hemoglobin and iron, proposed to induce endothelial dysfunction and impair host defense. There is noted vari...

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Detalles Bibliográficos
Autores principales: Osei-Hwedieh, David O., Kanias, Tamir, Croix, Claudette St., Jessup, Morgan, Xiong, Zeyu, Sinchar, Derek, Franks, Jonathan, Xu, Qinzi, M. Novelli, Enrico, Sertorio, Jonas T., Potoka, Karin, Binder, Robert J., Basu, Swati, Belanger, Andrea M., Kim-Shapiro, Daniel B., Triulzi, Darrell, Lee, Janet S., Gladwin, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049931/
https://www.ncbi.nlm.nih.gov/pubmed/27523807
http://dx.doi.org/10.1016/j.ebiom.2016.08.006

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