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(13)C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids

Efficient redirection of microbial metabolism into the abundant production of desired bioproducts remains non-trivial. Here, we used flux-based modeling approaches to improve yields of fatty acids in Saccharomyces cerevisiae. We combined (13)C labeling data with comprehensive genome-scale models to...

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Detalles Bibliográficos
Autores principales:	Ghosh, Amit, Ando, David, Gin, Jennifer, Runguphan, Weerawat, Denby, Charles, Wang, George, Baidoo, Edward E. K., Shymansky, Chris, Keasling, Jay D., García Martín, Héctor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050205/ https://www.ncbi.nlm.nih.gov/pubmed/27761435 http://dx.doi.org/10.3389/fbioe.2016.00076

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