Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis

Functionally compromised neutrophils contribute to adverse clinical outcomes in patients with severe inflammation and injury such as colitis and sepsis. However, the ontogeny of dysfunctional neutrophil during septic colitis remain poorly understood. We report that the dysfunctional neutrophil may b...

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Detalles Bibliográficos
Autores principales: Diao, Na, Zhang, Yao, Chen, Keqiang, Yuan, Ruoxi, Lee, Christina, Geng, Shuo, Kowalski, Elizabeth, Guo, Wen, Xiong, Huabao, Li, Mingsong, Li, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050405/
https://www.ncbi.nlm.nih.gov/pubmed/27703259
http://dx.doi.org/10.1038/srep34672

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