A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human Primates

Dengue virus has emerged as an important arboviral infection worldwide. As a complex pathogen, with four distinct serotypes, the development of a successful Dengue virus vaccine has proven to be challenging. Here, we describe a novel Dengue vaccine candidate that contains truncated, recombinant, Den...

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Detalles Bibliográficos
Autores principales: Swaminathan, Gokul, Thoryk, Elizabeth A., Cox, Kara S., Smith, Jeffrey S., Wolf, Jayanthi J., Gindy, Marian E., Casimiro, Danilo R., Bett, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050434/
https://www.ncbi.nlm.nih.gov/pubmed/27703172
http://dx.doi.org/10.1038/srep34215

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