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Necrostatin-1 treatment inhibits osteocyte necroptosis and trabecular deterioration in ovariectomized rats
Estrogen (E2) deficiency has been associated with accelerated osteocyte apoptosis. Our previous study showed necroptosis accelerated the loss of osteocytes in E2 deficiency-induced osteoporosis in rats in addition to apoptosis, but the mechanism involved remains. Necroptosis is a caspase-independent...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050438/ https://www.ncbi.nlm.nih.gov/pubmed/27703177 http://dx.doi.org/10.1038/srep33803 |