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Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways

The aim of this study is to elucidate to what degree adiponectin is involved in TZD-mediated amelioration of neointimal formation. We investigated the effect of 3- or 8-weeks’ pioglitazone on cuff-induced neointimal formation in adiponectin-deficient (APN-KO) and wild-type (WT) mice. Pioglitazone fo...

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Detalles Bibliográficos
Autores principales:	Kubota, Tetsuya, Kubota, Naoto, Sato, Hiroyuki, Inoue, Mariko, Kumagai, Hiroki, Iwamura, Tomokatsu, Takamoto, Iseki, Kobayashi, Tsuneo, Moroi, Masao, Terauchi, Yasuo, Tobe, Kazuyuki, Ueki, Kohjiro, Kadowaki, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050439/ https://www.ncbi.nlm.nih.gov/pubmed/27703271 http://dx.doi.org/10.1038/srep34707

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