Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes

The glucagon-like peptide (GLP)-1 receptor (GLP-1R) is a class B G protein–coupled receptor (GPCR) that mediates the action of GLP-1, a peptide hormone secreted from three major tissues in humans, enteroendocrine L cells in the distal intestine, α cells in the pancreas, and the central nervous syste...

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Detalles Bibliográficos
Autores principales: de Graaf, Chris, Donnelly, Dan, Wootten, Denise, Lau, Jesper, Sexton, Patrick M., Miller, Laurence J., Ahn, Jung-Mo, Liao, Jiayu, Fletcher, Madeleine M., Yang, Dehua, Brown, Alastair J. H., Zhou, Caihong, Deng, Jiejie, Wang, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050443/
https://www.ncbi.nlm.nih.gov/pubmed/27630114
http://dx.doi.org/10.1124/pr.115.011395

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