Cargando…

The Principles of Ligand Specificity on beta-2-adrenergic receptor

G protein-coupled receptors are recognized as one of the largest families of membrane proteins. Despite sharing a characteristic seven-transmembrane topology, G protein-coupled receptors regulate a wide range of cellular signaling pathways in response to various physical and chemical stimuli, and pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, H. C. Stephen, Filipek, Slawomir, Yuan, Shuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050457/ https://www.ncbi.nlm.nih.gov/pubmed/27703221 http://dx.doi.org/10.1038/srep34736

Ejemplares similares

Exchanging ligand-binding specificity between a pair of mouse olfactory receptor paralogs reveals odorant recognition principles
por: Baud, Olivia, et al.
Publicado: (2015)

Exploring a new ligand binding site of G protein-coupled receptors
por: Chan, H. C. Stephen, et al.
Publicado: (2018)

The Molecular Mechanism of P2Y(1) Receptor Activation
por: Yuan, Shuguang, et al.
Publicado: (2016)

Unconventional interactions of the TRPV4 ion channel with beta-adrenergic receptor ligands
por: Benítez-Angeles, Miguel, et al.
Publicado: (2022)

Mechanistic Studies on the Stereoselectivity of the Serotonin 5‐HT(1A) Receptor
por: Yuan, Shuguang, et al.
Publicado: (2016)

The Role of Beta-Adrenergic Receptors in Depression and Resilience
por: Zhang, Hongxing, et al.
Publicado: (2022)

Computational modeling of the olfactory receptor Olfr73 suggests a molecular basis for low potency of olfactory receptor-activating compounds
por: Yuan, Shuguang, et al.
Publicado: (2019)

Lipid Receptor S1P(1) Activation Scheme Concluded from Microsecond All-Atom Molecular Dynamics Simulations
por: Yuan, Shuguang, et al.
Publicado: (2013)

Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
por: Chen, Yue, et al.
Publicado: (2021)

Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function
por: Petkevicius, Kasparas, et al.
Publicado: (2021)

Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors
por: González, Angel, et al.
Publicado: (2011)

Morphology of astroglial cells is controlled by beta-adrenergic receptors
Publicado: (1987)

Alpha and beta adrenergic receptors modulate keratinocyte migration
por: Yang, Hsin-ya, et al.
Publicado: (2021)

Beta-adrenergic receptor blockade in angiosarcoma: Which beta-blocker to choose?
por: Embaby, Alaa, et al.
Publicado: (2022)

Mutual Enhancement of Opioid and Adrenergic Receptors by Combinations of Opioids and Adrenergic Ligands Is Reflected in Molecular Complementarity of Ligands: Drug Development Possibilities
por: Root-Bernstein, Robert, et al.
Publicado: (2019)

Beta-Adrenergic Agonists
por: Barisione, Giovanni, et al.
Publicado: (2010)

Ligands of Adrenergic Receptors: A Structural Point of View
por: Wu, Yiran, et al.
Publicado: (2021)

Beta-adrenergic receptors are expressed across diverse cancers
por: Rains, Steven L., et al.
Publicado: (2017)

Dissecting Beta-Adrenergic Receptors: The Sum of Many Parts
por: Port, J. David
Publicado: (2023)

Beta(1)-Adrenergic Receptor Cleavage and Regulation by Elastase
por: Zhu, Jing, et al.
Publicado: (2023)

Quantification of Beta Adrenergic Receptor Subtypes in Beta-Arrestin Knockout Mouse Airways
por: Hegde, Akhil, et al.
Publicado: (2015)

The effects of beta2 adrenergic receptor gene polymorphism in lipid profiles
por: Kao, Wei-Tsung, et al.
Publicado: (2008)

Structural insights into ligand recognition, activation, and signaling of the α(2A) adrenergic receptor
por: Xu, Jun, et al.
Publicado: (2022)

Beta 1, Beta 2 and Beta 3 Adrenergic Receptor Gene Polymorphisms in a Southeastern European Population
por: Katsarou, Martha-Spyridoula, et al.
Publicado: (2018)

Structural Features and Ligand Selectivity for 10 Intermediates in the Activation Process of β(2)-Adrenergic Receptor
por: Liang, Tao, et al.
Publicado: (2017)

Beta 2-adrenergic receptor activation enhances neurogenesis in Alzheimer's disease mice
por: Chai, Gao-shang, et al.
Publicado: (2016)

Association of polymorphisms in the beta-2 adrenergic receptor gene with fracture risk and bone mineral density
por: Veldhuis-Vlug, A. G., et al.
Publicado: (2015)

The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms
por: quốc Lu’o’ng, Khanh vinh, et al.
Publicado: (2012)

Cardiac physiologic regulation of sub-type specific adrenergic receptors in transgenic mice overexpressing β(1)- and β(2)-adrenergic receptors
por: Kim, Ka Eul, et al.
Publicado: (2016)

Stimulation of the beta-2-adrenergic receptor with salbutamol activates human brown adipose tissue
por: Straat, Maaike E., et al.
Publicado: (2023)

Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation
por: Petkevicius, Kasparas, et al.
Publicado: (2021)

Beta-adrenergic receptor antagonists and chronic heart failure in children
por: Filippo, Sylvie Di
Publicado: (2007)

The Beta3 Adrenergic Receptor in Healthy and Pathological Cardiovascular Tissues
por: Michel, Lauriane Y. M., et al.
Publicado: (2020)

Evaluation of spirometry values in relation to beta-2-adrenergic receptor gene polymorphism
por: Poziomkowska-Gesicka, I, et al.
Publicado: (2010)

INCREASED BETA2-ADRENERGIC RECEPTOR SIGNALING ENHANCES PROGRESSION OF HEPATOCELLULAR CARCINOMA
por: Pizzini, Jason, et al.
Publicado: (2019)

De Novo BETA-2 adrenergic receptor gene variant associated with obesity
por: Yaman Kalender, Derya Sema, et al.
Publicado: (2023)

Role of beta-adrenergic receptor subtypes in pig uterus contractility with inflammation
por: Jana, Barbara, et al.
Publicado: (2021)

The Glu27 genotypes of the Beta2-adrenergic receptor are predictors for severe coronary artery disease
por: Abu-Amero, Khaled K, et al.
Publicado: (2006)

Influence of polymorphisms of the beta-2 adrenergic receptor on the presence of exercise-induced bronchospasm in adolescents✰
por: Consentino, Cássio Leandro Mühe, et al.
Publicado: (2016)

Association of beta(2)-adrenergic receptor gene polymorphisms and nocturnal asthma in Saudi patients
por: Al-Rubaish, Abdullah M.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_p0cnfmipicvhdhd0g71kgghflt