Ebola Virus Epidemiology and Evolution in Nigeria

Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly compl...

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Autores principales: Folarin, Onikepe A., Ehichioya, Deborah, Schaffner, Stephen F., Winnicki, Sarah M., Wohl, Shirlee, Eromon, Philomena, West, Kendra L., Gladden-Young, Adrianne, Oyejide, Nicholas E., Matranga, Christian B., Deme, Awa Bineta, James, Ayorinde, Tomkins-Tinch, Christopher, Onyewurunwa, Kenneth, Ladner, Jason T., Palacios, Gustavo, Nosamiefan, Iguosadolo, Andersen, Kristian G., Omilabu, Sunday, Park, Daniel J., Yozwiak, Nathan L., Nasidi, Abdusallam, Garry, Robert F., Tomori, Oyewale, Sabeti, Pardis C., Happi, Christian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Ebola Outbreak in West Africa
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050462/
https://www.ncbi.nlm.nih.gov/pubmed/27377746
http://dx.doi.org/10.1093/infdis/jiw190
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author Folarin, Onikepe A.
Ehichioya, Deborah
Schaffner, Stephen F.
Winnicki, Sarah M.
Wohl, Shirlee
Eromon, Philomena
West, Kendra L.
Gladden-Young, Adrianne
Oyejide, Nicholas E.
Matranga, Christian B.
Deme, Awa Bineta
James, Ayorinde
Tomkins-Tinch, Christopher
Onyewurunwa, Kenneth
Ladner, Jason T.
Palacios, Gustavo
Nosamiefan, Iguosadolo
Andersen, Kristian G.
Omilabu, Sunday
Park, Daniel J.
Yozwiak, Nathan L.
Nasidi, Abdusallam
Garry, Robert F.
Tomori, Oyewale
Sabeti, Pardis C.
Happi, Christian T.
author_facet Folarin, Onikepe A.
Ehichioya, Deborah
Schaffner, Stephen F.
Winnicki, Sarah M.
Wohl, Shirlee
Eromon, Philomena
West, Kendra L.
Gladden-Young, Adrianne
Oyejide, Nicholas E.
Matranga, Christian B.
Deme, Awa Bineta
James, Ayorinde
Tomkins-Tinch, Christopher
Onyewurunwa, Kenneth
Ladner, Jason T.
Palacios, Gustavo
Nosamiefan, Iguosadolo
Andersen, Kristian G.
Omilabu, Sunday
Park, Daniel J.
Yozwiak, Nathan L.
Nasidi, Abdusallam
Garry, Robert F.
Tomori, Oyewale
Sabeti, Pardis C.
Happi, Christian T.
author_sort Folarin, Onikepe A.
collection PubMed
description Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.
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spelling pubmed-50504622016-10-06 Ebola Virus Epidemiology and Evolution in Nigeria Folarin, Onikepe A. Ehichioya, Deborah Schaffner, Stephen F. Winnicki, Sarah M. Wohl, Shirlee Eromon, Philomena West, Kendra L. Gladden-Young, Adrianne Oyejide, Nicholas E. Matranga, Christian B. Deme, Awa Bineta James, Ayorinde Tomkins-Tinch, Christopher Onyewurunwa, Kenneth Ladner, Jason T. Palacios, Gustavo Nosamiefan, Iguosadolo Andersen, Kristian G. Omilabu, Sunday Park, Daniel J. Yozwiak, Nathan L. Nasidi, Abdusallam Garry, Robert F. Tomori, Oyewale Sabeti, Pardis C. Happi, Christian T. J Infect Dis Ebola Outbreak in West Africa Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur. Oxford University Press 2016-10-15 2016-10-04 /pmc/articles/PMC5050462/ /pubmed/27377746 http://dx.doi.org/10.1093/infdis/jiw190 Text en © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial reuse, contact journals.permissions@oup.com.
spellingShingle Ebola Outbreak in West Africa
Folarin, Onikepe A.
Ehichioya, Deborah
Schaffner, Stephen F.
Winnicki, Sarah M.
Wohl, Shirlee
Eromon, Philomena
West, Kendra L.
Gladden-Young, Adrianne
Oyejide, Nicholas E.
Matranga, Christian B.
Deme, Awa Bineta
James, Ayorinde
Tomkins-Tinch, Christopher
Onyewurunwa, Kenneth
Ladner, Jason T.
Palacios, Gustavo
Nosamiefan, Iguosadolo
Andersen, Kristian G.
Omilabu, Sunday
Park, Daniel J.
Yozwiak, Nathan L.
Nasidi, Abdusallam
Garry, Robert F.
Tomori, Oyewale
Sabeti, Pardis C.
Happi, Christian T.
Ebola Virus Epidemiology and Evolution in Nigeria
title Ebola Virus Epidemiology and Evolution in Nigeria
title_full Ebola Virus Epidemiology and Evolution in Nigeria
title_fullStr Ebola Virus Epidemiology and Evolution in Nigeria
title_full_unstemmed Ebola Virus Epidemiology and Evolution in Nigeria
title_short Ebola Virus Epidemiology and Evolution in Nigeria
title_sort ebola virus epidemiology and evolution in nigeria
topic Ebola Outbreak in West Africa
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050462/
https://www.ncbi.nlm.nih.gov/pubmed/27377746
http://dx.doi.org/10.1093/infdis/jiw190
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