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Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly
Malonyl carba(dethia) N-decanoyl cysteamine methyl esters and novel acetoxymethyl esters were utilised as second-generation probes for polyketide intermediate capture. The use of these tools in vivo led to the characterisation of an almost complete set of biosynthetic intermediates from a modular as...
Autores principales: | Wilkening, Ina, Gazzola, Silvia, Riva, Elena, Parascandolo, James S., Song, Lijiang, Tosin, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050551/ https://www.ncbi.nlm.nih.gov/pubmed/27481638 http://dx.doi.org/10.1039/c6cc04681a |
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