A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis

BACKGROUND: Toll-like receptor (TLR) family members are key players in inflammation. TLR10 has been poorly studied in chronic inflammatory disorders, and its clinical relevance in rheumatoid arthritis (RA) is as yet unknown. We aimed at identifying TLR10 variants within all coding regions of the gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Torices, Silvia, Julia, Antonio, Muñoz, Pedro, Varela, Ignacio, Balsa, Alejandro, Marsal, Sara, Fernández-Nebro, Antonio, Blanco, Francisco, López-Hoyos, Marcos, Martinez-Taboada, Víctor, Fernández-Luna, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050569/
https://www.ncbi.nlm.nih.gov/pubmed/27716427
http://dx.doi.org/10.1186/s13075-016-1113-z

Ejemplares similares

Ejemplares similares