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Simulating cryo electron tomograms of crowded cell cytoplasm for assessment of automated particle picking
BACKGROUND: Cryo-electron tomography is an important tool to study structures of macromolecular complexes in close to native states. A whole cell cryo electron tomogram contains structural information of all its macromolecular complexes. However, extracting this information remains challenging, and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050594/ https://www.ncbi.nlm.nih.gov/pubmed/27716029 http://dx.doi.org/10.1186/s12859-016-1283-3 |