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Simulating cryo electron tomograms of crowded cell cytoplasm for assessment of automated particle picking

BACKGROUND: Cryo-electron tomography is an important tool to study structures of macromolecular complexes in close to native states. A whole cell cryo electron tomogram contains structural information of all its macromolecular complexes. However, extracting this information remains challenging, and...

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Detalles Bibliográficos
Autores principales:	Pei, Long, Xu, Min, Frazier, Zachary, Alber, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050594/ https://www.ncbi.nlm.nih.gov/pubmed/27716029 http://dx.doi.org/10.1186/s12859-016-1283-3

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