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miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1

BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNAs that are emerging as important post-transcriptional regulators of neuronal and synaptic development. The precise impact of miRNAs on presynaptic function and neurotransmission remains, however, poorly understood. RESULTS: Here, we identify miR...

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Detalles Bibliográficos
Autores principales: Poon, Vivian Y., Gu, Minxia, Ji, Fang, VanDongen, Antonius M., Fivaz, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050705/
https://www.ncbi.nlm.nih.gov/pubmed/27716060
http://dx.doi.org/10.1186/s12864-016-3139-7