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The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study

CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian...

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Autores principales: Mendsaikhan, Naranpurev, Begzjav, Tsolmon, Lundeg, Ganbold, Dünser, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051051/
https://www.ncbi.nlm.nih.gov/pubmed/27722110
http://dx.doi.org/10.4103/2229-5151.190657
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author Mendsaikhan, Naranpurev
Begzjav, Tsolmon
Lundeg, Ganbold
Dünser, Martin W.
author_facet Mendsaikhan, Naranpurev
Begzjav, Tsolmon
Lundeg, Ganbold
Dünser, Martin W.
author_sort Mendsaikhan, Naranpurev
collection PubMed
description CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian centers. MATERIALS AND METHODS: Demographic, clinical, and outcome data of patients >15 years admitted to the Intensive Care Units (ICUs) were collected during a 6-month period. STATISTICAL ANALYSIS: Descriptive methods, Mann–Whitney-U test, Fisher's exact or Chi-square test, and logistic regression analyses were used for statistical analysis. RESULTS: Two thousand and thirty-two patients (53.6% male) with a median age of 49 years (36–62 years) were included. The most frequent ICU admission diagnoses were stroke (17.4%), liver failure (9.2%), heart failure (9%), infection (8.3%), severe trauma (7.5%), traumatic brain injury (7.1%), acute abdomen (7%), pre-eclampsia/eclampsia (5.8%), renal failure (3.9%), and postoperative care following elective and emergency surgeries (3.2%). ICU mortality was 23.5% in the study population and 26.6% when maternal cases were excluded. The five ICU admission diagnoses with the highest ICU mortality were lung tuberculosis (51.9%), traumatic brain injury (42.1%), liver failure (33.7%), stroke (31.9%), and infection (30.8%). The five ICU admission diagnoses causing most death cases were stroke (n = 113), liver failure (n = 63), traumatic brain injury (n = 61), infection (n = 52), and acute abdomen (n = 38). CONCLUSION: Critical illness in Mongolia affects younger patients compared to high-income countries. ICU admission diagnoses are similar with a particularly high incidence of stroke and liver failure. ICU mortality is approximately 25% with most deaths caused by stroke, liver failure, and traumatic brain injury.
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spelling pubmed-50510512016-10-07 The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study Mendsaikhan, Naranpurev Begzjav, Tsolmon Lundeg, Ganbold Dünser, Martin W. Int J Crit Illn Inj Sci Original Article CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian centers. MATERIALS AND METHODS: Demographic, clinical, and outcome data of patients >15 years admitted to the Intensive Care Units (ICUs) were collected during a 6-month period. STATISTICAL ANALYSIS: Descriptive methods, Mann–Whitney-U test, Fisher's exact or Chi-square test, and logistic regression analyses were used for statistical analysis. RESULTS: Two thousand and thirty-two patients (53.6% male) with a median age of 49 years (36–62 years) were included. The most frequent ICU admission diagnoses were stroke (17.4%), liver failure (9.2%), heart failure (9%), infection (8.3%), severe trauma (7.5%), traumatic brain injury (7.1%), acute abdomen (7%), pre-eclampsia/eclampsia (5.8%), renal failure (3.9%), and postoperative care following elective and emergency surgeries (3.2%). ICU mortality was 23.5% in the study population and 26.6% when maternal cases were excluded. The five ICU admission diagnoses with the highest ICU mortality were lung tuberculosis (51.9%), traumatic brain injury (42.1%), liver failure (33.7%), stroke (31.9%), and infection (30.8%). The five ICU admission diagnoses causing most death cases were stroke (n = 113), liver failure (n = 63), traumatic brain injury (n = 61), infection (n = 52), and acute abdomen (n = 38). CONCLUSION: Critical illness in Mongolia affects younger patients compared to high-income countries. ICU admission diagnoses are similar with a particularly high incidence of stroke and liver failure. ICU mortality is approximately 25% with most deaths caused by stroke, liver failure, and traumatic brain injury. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5051051/ /pubmed/27722110 http://dx.doi.org/10.4103/2229-5151.190657 Text en Copyright: © 2016 International Journal of Critical Illness and Injury Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mendsaikhan, Naranpurev
Begzjav, Tsolmon
Lundeg, Ganbold
Dünser, Martin W.
The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title_full The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title_fullStr The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title_full_unstemmed The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title_short The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
title_sort epidemiology and outcome of critical illness in mongolia: a multicenter, prospective, observational cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051051/
https://www.ncbi.nlm.nih.gov/pubmed/27722110
http://dx.doi.org/10.4103/2229-5151.190657
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