Cargando…
The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study
CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051051/ https://www.ncbi.nlm.nih.gov/pubmed/27722110 http://dx.doi.org/10.4103/2229-5151.190657 |
_version_ | 1782458005251424256 |
---|---|
author | Mendsaikhan, Naranpurev Begzjav, Tsolmon Lundeg, Ganbold Dünser, Martin W. |
author_facet | Mendsaikhan, Naranpurev Begzjav, Tsolmon Lundeg, Ganbold Dünser, Martin W. |
author_sort | Mendsaikhan, Naranpurev |
collection | PubMed |
description | CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian centers. MATERIALS AND METHODS: Demographic, clinical, and outcome data of patients >15 years admitted to the Intensive Care Units (ICUs) were collected during a 6-month period. STATISTICAL ANALYSIS: Descriptive methods, Mann–Whitney-U test, Fisher's exact or Chi-square test, and logistic regression analyses were used for statistical analysis. RESULTS: Two thousand and thirty-two patients (53.6% male) with a median age of 49 years (36–62 years) were included. The most frequent ICU admission diagnoses were stroke (17.4%), liver failure (9.2%), heart failure (9%), infection (8.3%), severe trauma (7.5%), traumatic brain injury (7.1%), acute abdomen (7%), pre-eclampsia/eclampsia (5.8%), renal failure (3.9%), and postoperative care following elective and emergency surgeries (3.2%). ICU mortality was 23.5% in the study population and 26.6% when maternal cases were excluded. The five ICU admission diagnoses with the highest ICU mortality were lung tuberculosis (51.9%), traumatic brain injury (42.1%), liver failure (33.7%), stroke (31.9%), and infection (30.8%). The five ICU admission diagnoses causing most death cases were stroke (n = 113), liver failure (n = 63), traumatic brain injury (n = 61), infection (n = 52), and acute abdomen (n = 38). CONCLUSION: Critical illness in Mongolia affects younger patients compared to high-income countries. ICU admission diagnoses are similar with a particularly high incidence of stroke and liver failure. ICU mortality is approximately 25% with most deaths caused by stroke, liver failure, and traumatic brain injury. |
format | Online Article Text |
id | pubmed-5051051 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-50510512016-10-07 The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study Mendsaikhan, Naranpurev Begzjav, Tsolmon Lundeg, Ganbold Dünser, Martin W. Int J Crit Illn Inj Sci Original Article CONTEXT: The epidemiology and outcome of critical illness in Mongolia remain undefined. AIM: The aim of this study was to evaluate the epidemiology and outcome of critical illness in Mongolia. SETTINGS AND DESIGN: This is a multicenter, prospective, observational cohort study including 19 Mongolian centers. MATERIALS AND METHODS: Demographic, clinical, and outcome data of patients >15 years admitted to the Intensive Care Units (ICUs) were collected during a 6-month period. STATISTICAL ANALYSIS: Descriptive methods, Mann–Whitney-U test, Fisher's exact or Chi-square test, and logistic regression analyses were used for statistical analysis. RESULTS: Two thousand and thirty-two patients (53.6% male) with a median age of 49 years (36–62 years) were included. The most frequent ICU admission diagnoses were stroke (17.4%), liver failure (9.2%), heart failure (9%), infection (8.3%), severe trauma (7.5%), traumatic brain injury (7.1%), acute abdomen (7%), pre-eclampsia/eclampsia (5.8%), renal failure (3.9%), and postoperative care following elective and emergency surgeries (3.2%). ICU mortality was 23.5% in the study population and 26.6% when maternal cases were excluded. The five ICU admission diagnoses with the highest ICU mortality were lung tuberculosis (51.9%), traumatic brain injury (42.1%), liver failure (33.7%), stroke (31.9%), and infection (30.8%). The five ICU admission diagnoses causing most death cases were stroke (n = 113), liver failure (n = 63), traumatic brain injury (n = 61), infection (n = 52), and acute abdomen (n = 38). CONCLUSION: Critical illness in Mongolia affects younger patients compared to high-income countries. ICU admission diagnoses are similar with a particularly high incidence of stroke and liver failure. ICU mortality is approximately 25% with most deaths caused by stroke, liver failure, and traumatic brain injury. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5051051/ /pubmed/27722110 http://dx.doi.org/10.4103/2229-5151.190657 Text en Copyright: © 2016 International Journal of Critical Illness and Injury Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Mendsaikhan, Naranpurev Begzjav, Tsolmon Lundeg, Ganbold Dünser, Martin W. The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title | The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title_full | The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title_fullStr | The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title_full_unstemmed | The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title_short | The epidemiology and outcome of critical illness in Mongolia: A multicenter, prospective, observational cohort study |
title_sort | epidemiology and outcome of critical illness in mongolia: a multicenter, prospective, observational cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051051/ https://www.ncbi.nlm.nih.gov/pubmed/27722110 http://dx.doi.org/10.4103/2229-5151.190657 |
work_keys_str_mv | AT mendsaikhannaranpurev theepidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT begzjavtsolmon theepidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT lundegganbold theepidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT dunsermartinw theepidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT mendsaikhannaranpurev epidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT begzjavtsolmon epidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT lundegganbold epidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy AT dunsermartinw epidemiologyandoutcomeofcriticalillnessinmongoliaamulticenterprospectiveobservationalcohortstudy |