Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases

Clostridium difficile associated diarrhoea has been an increasing problem in the last decade in the UK and is a cause of significant morbidity. At the most severe end of the spectrum it causes pseudomembranous colitis which has a significant associated mortality rate and can be refractory to standar...

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Detalles Bibliográficos
Autores principales: Sykes, Ella, McDonald, Patrick, Flanagan, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051105/
https://www.ncbi.nlm.nih.gov/pubmed/27785209
http://dx.doi.org/10.4021/gr469w
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author Sykes, Ella
McDonald, Patrick
Flanagan, Paul K.
author_facet Sykes, Ella
McDonald, Patrick
Flanagan, Paul K.
author_sort Sykes, Ella
collection PubMed
description Clostridium difficile associated diarrhoea has been an increasing problem in the last decade in the UK and is a cause of significant morbidity. At the most severe end of the spectrum it causes pseudomembranous colitis which has a significant associated mortality rate and can be refractory to standard treatments. Here we present three cases of proven pseudomembranous colitis in which systemic corticosteroids were used as an adjunct to treatment, raising the possibility of a new treatment option for this difficult condition.
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spelling pubmed-50511052016-10-26 Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases Sykes, Ella McDonald, Patrick Flanagan, Paul K. Gastroenterology Res Case Report Clostridium difficile associated diarrhoea has been an increasing problem in the last decade in the UK and is a cause of significant morbidity. At the most severe end of the spectrum it causes pseudomembranous colitis which has a significant associated mortality rate and can be refractory to standard treatments. Here we present three cases of proven pseudomembranous colitis in which systemic corticosteroids were used as an adjunct to treatment, raising the possibility of a new treatment option for this difficult condition. Elmer Press 2012-10 2012-09-20 /pmc/articles/PMC5051105/ /pubmed/27785209 http://dx.doi.org/10.4021/gr469w Text en Copyright 2012, Sykes et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sykes, Ella
McDonald, Patrick
Flanagan, Paul K.
Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title_full Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title_fullStr Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title_full_unstemmed Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title_short Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases
title_sort corticosteroids in the treatment of pseudomembranous colitis: a report of 3 cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051105/
https://www.ncbi.nlm.nih.gov/pubmed/27785209
http://dx.doi.org/10.4021/gr469w
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