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Using serum urate as a validated surrogate end point for flares in patients with gout: protocol for a systematic review and meta-regression analysis

INTRODUCTION: Gout is the most common inflammatory arthritis in men over 40 years of age. Long-term urate-lowering therapy is considered a key strategy for effective gout management. The primary outcome measure for efficacy in clinical trials of urate-lowering therapy is serum urate levels, effectiv...

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Detalles Bibliográficos
Autores principales:	Morillon, Melanie B, Stamp, Lisa, Taylor, William, Fransen, Jaap, Dalbeth, Nicola, Singh, Jasvinder A, Christensen, Robin, Lassere, Marissa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Rheumatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051435/ https://www.ncbi.nlm.nih.gov/pubmed/27650765 http://dx.doi.org/10.1136/bmjopen-2016-012026

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