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The surface of the eye – a superficial entity with deep repercussions
The surface of the eye is an anatomical and functional entity with a relatively recent delimitation but with significant therapeutic and diagnostic consequences. The pathology of the conjunctive and cornea must be approached by looking at the interrelations between the two tissues that are so differ...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051484/ https://www.ncbi.nlm.nih.gov/pubmed/20108493 |
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author | Potop, Vasile Dumitrache, Marieta Ciocalteu, Alina |
author_facet | Potop, Vasile Dumitrache, Marieta Ciocalteu, Alina |
author_sort | Potop, Vasile |
collection | PubMed |
description | The surface of the eye is an anatomical and functional entity with a relatively recent delimitation but with significant therapeutic and diagnostic consequences. The pathology of the conjunctive and cornea must be approached by looking at the interrelations between the two tissues that are so different anatomically and functionally but in the same time form a unit in structuring the eye’s surface. There are two major categories of relations between the two tissues: one of them is mediated by lachrymal secretion, a process whose complexity is not yet fully understood, and the other is germinal, referring to the stem cells located at the limbus which become epithelial cornea cells that can fixate lachrymal fluid. Imbalances in the quantity and quality of lachrymal secretion can be compensated, up to a certain point, by artificial products, but in severe cases only specially prepared autologous serum can compensate the deficit. The limbic deficits that affect stem cells require complex therapeutic procedures like limbic cell transplant, using an amniotic membrane or autologous serum. |
format | Online Article Text |
id | pubmed-5051484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-50514842016-10-21 The surface of the eye – a superficial entity with deep repercussions Potop, Vasile Dumitrache, Marieta Ciocalteu, Alina J Med Life General Articles The surface of the eye is an anatomical and functional entity with a relatively recent delimitation but with significant therapeutic and diagnostic consequences. The pathology of the conjunctive and cornea must be approached by looking at the interrelations between the two tissues that are so different anatomically and functionally but in the same time form a unit in structuring the eye’s surface. There are two major categories of relations between the two tissues: one of them is mediated by lachrymal secretion, a process whose complexity is not yet fully understood, and the other is germinal, referring to the stem cells located at the limbus which become epithelial cornea cells that can fixate lachrymal fluid. Imbalances in the quantity and quality of lachrymal secretion can be compensated, up to a certain point, by artificial products, but in severe cases only specially prepared autologous serum can compensate the deficit. The limbic deficits that affect stem cells require complex therapeutic procedures like limbic cell transplant, using an amniotic membrane or autologous serum. Carol Davila University Press 2009 /pmc/articles/PMC5051484/ /pubmed/20108493 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | General Articles Potop, Vasile Dumitrache, Marieta Ciocalteu, Alina The surface of the eye – a superficial entity with deep repercussions |
title | The surface of the eye – a superficial entity with deep repercussions
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title_full | The surface of the eye – a superficial entity with deep repercussions
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title_fullStr | The surface of the eye – a superficial entity with deep repercussions
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title_full_unstemmed | The surface of the eye – a superficial entity with deep repercussions
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title_short | The surface of the eye – a superficial entity with deep repercussions
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title_sort | surface of the eye – a superficial entity with deep repercussions |
topic | General Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051484/ https://www.ncbi.nlm.nih.gov/pubmed/20108493 |
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