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Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro

Protein kinase C α (PKCα) is a nodal regulator in several intracellular signaling networks. PKCα is composed of modular domains that interact with each other to dynamically regulate spatial-temporal function. We find that PKCα specifically, rapidly and reversibly self-assembles in the presence of ca...

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Detalles Bibliográficos
Autores principales:	Swanson, Carter J., Sommese, Ruth F., Petersen, Karl J., Ritt, Michael, Karslake, Joshua, Thomas, David D., Sivaramakrishnan, Sivaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051681/ https://www.ncbi.nlm.nih.gov/pubmed/27706148 http://dx.doi.org/10.1371/journal.pone.0162331

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