Spatial and Temporal Resolution of Global Protein Synthesis during HSV Infection Using Bioorthogonal Precursors and Click Chemistry

We used pulse-labeling with the methionine analogue homopropargylglycine (HPG) to investigate spatiotemporal aspects of protein synthesis during herpes simplex virus (HSV) infection. In vivo incorporation of HPG enables subsequent selective coupling of fluorochrome-capture reagents to newly synthesi...

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Detalles Bibliográficos
Autores principales: Su Hui Teo, Catherine, Serwa, Remigiusz A., O’Hare, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051704/
https://www.ncbi.nlm.nih.gov/pubmed/27706239
http://dx.doi.org/10.1371/journal.ppat.1005927

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