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Augmented Growth Hormone Secretion and Stat3 Phosphorylation in an Aryl Hydrocarbon Receptor Interacting Protein (AIP)-Disrupted Somatotroph Cell Line

Aryl hydrocarbon receptor interacting protein (AIP) is thought to be a tumor suppressor gene, as indicated by a mutational analysis of pituitary somatotroph adenomas. However, the physiological significance of AIP inactivation in somatotroph cells remains unclear. Using CRISPR/Cas9, we identified a...

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Detalles Bibliográficos
Autores principales:	Fukuda, Takashi, Tanaka, Tomoko, Hamaguchi, Yuriko, Kawanami, Takako, Nomiyama, Takashi, Yanase, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051713/ https://www.ncbi.nlm.nih.gov/pubmed/27706259 http://dx.doi.org/10.1371/journal.pone.0164131

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