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Mechanism of Rifampicin Inactivation in Nocardia farcinica

A novel mechanism of rifampicin (Rif) resistance has recently been reported in Nocardia farcinica. This new mechanism involves the activity of rifampicin monooxygenase (RifMO), a flavin-dependent monooxygenase that catalyzes the hydroxylation of Rif, which is the first step in the degradation pathwa...

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Detalles Bibliográficos
Autores principales: Abdelwahab, Heba, Martin Del Campo, Julia S., Dai, Yumin, Adly, Camelia, El-Sohaimy, Sohby, Sobrado, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051949/
https://www.ncbi.nlm.nih.gov/pubmed/27706151
http://dx.doi.org/10.1371/journal.pone.0162578