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Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease

For many neurological and psychiatric diseases, novel therapeutics have been elusive for decades. By focusing on attention interference in Alzheimer's disease (AD), we provide a future vision on how emerging mobile, computer, and device‐based cognitive tools are converting classically noisy, su...

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Detalles Bibliográficos
Autores principales: Leurent, C, Ehlers, MD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052022/
https://www.ncbi.nlm.nih.gov/pubmed/26272508
http://dx.doi.org/10.1002/cpt.212
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author Leurent, C
Ehlers, MD
author_facet Leurent, C
Ehlers, MD
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description For many neurological and psychiatric diseases, novel therapeutics have been elusive for decades. By focusing on attention interference in Alzheimer's disease (AD), we provide a future vision on how emerging mobile, computer, and device‐based cognitive tools are converting classically noisy, subjective, data‐poor clinical endpoints associated with neuropsychiatric disease assessment into a richer, scalable, and objective set of measurements. Incorporation of such endpoints into clinical drug trials holds promise for more quickly and efficiently developing new medicines.
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spelling pubmed-50520222016-10-06 Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease Leurent, C Ehlers, MD Clin Pharmacol Ther Development For many neurological and psychiatric diseases, novel therapeutics have been elusive for decades. By focusing on attention interference in Alzheimer's disease (AD), we provide a future vision on how emerging mobile, computer, and device‐based cognitive tools are converting classically noisy, subjective, data‐poor clinical endpoints associated with neuropsychiatric disease assessment into a richer, scalable, and objective set of measurements. Incorporation of such endpoints into clinical drug trials holds promise for more quickly and efficiently developing new medicines. John Wiley and Sons Inc. 2015-09-08 2015-11 /pmc/articles/PMC5052022/ /pubmed/26272508 http://dx.doi.org/10.1002/cpt.212 Text en © 2015 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals, Inc. on behalf of The American Society for Clinical Pharmacology and Therapeutics. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Development
Leurent, C
Ehlers, MD
Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title_full Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title_fullStr Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title_full_unstemmed Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title_short Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease
title_sort digital technologies for cognitive assessment to accelerate drug development in alzheimer's disease
topic Development
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052022/
https://www.ncbi.nlm.nih.gov/pubmed/26272508
http://dx.doi.org/10.1002/cpt.212
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