The nonessentiality of essential genes in yeast provides therapeutic insights into a human disease

Essential genes refer to those whose null mutation leads to lethality or sterility. Theoretical reasoning and empirical data both suggest that the fatal effect of inactivating an essential gene can be attributed to either the loss of indispensable core cellular function (Type I), or the gain of fata...

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Detalles Bibliográficos
Autores principales: Chen, Piaopiao, Wang, Dandan, Chen, Han, Zhou, Zhenzhen, He, Xionglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052060/
https://www.ncbi.nlm.nih.gov/pubmed/27440870
http://dx.doi.org/10.1101/gr.205955.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052060/
https://www.ncbi.nlm.nih.gov/pubmed/27440870
http://dx.doi.org/10.1101/gr.205955.116

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