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End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data
RNA-seq protocols that focus on transcript termini are well suited for applications in which template quantity is limiting. Here we show that, when applied to end-sequencing data, analytical methods designed for global RNA-seq produce computational artifacts. To remedy this, we created the End Seque...
Autores principales: | Derr, Alan, Yang, Chaoxing, Zilionis, Rapolas, Sergushichev, Alexey, Blodgett, David M., Redick, Sambra, Bortell, Rita, Luban, Jeremy, Harlan, David M., Kadener, Sebastian, Greiner, Dale L., Klein, Allon, Artyomov, Maxim N., Garber, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052061/ https://www.ncbi.nlm.nih.gov/pubmed/27470110 http://dx.doi.org/10.1101/gr.207902.116 |
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