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Metformin displays in vitro and in vivo antitumor effect against osteosarcoma

PURPOSE: Patients with unresectable, relapsed, or refractory osteosarcoma need a novel therapeutic agent. Metformin is a biguanide derivative used in the treatment of type II diabetes, and is recently gaining attention in cancer research. METHODS: We evaluated the effect of metformin against human o...

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Detalles Bibliográficos
Autores principales:	Ko, Yunmi, Choi, Aery, Lee, Minyoung, Lee, Jun Ah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Pediatric Society 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052136/ https://www.ncbi.nlm.nih.gov/pubmed/27721842 http://dx.doi.org/10.3345/kjp.2016.59.9.374

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