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NFAT2 Regulates Generation of Innate-Like CD8(+) T Lymphocytes and CD8(+) T Lymphocytes Responses

Nuclear factor of activated T cells (NFAT) 2 null mutant mice die in utero of cardiac failure, precluding analysis of the role of NFAT2 in lymphocyte responses. Only the NFAT2(−/−)/Rag-1(−/−) chimeric mice model gave insight into the role of NFAT2 transcription factor in T lymphocyte development, ac...

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Detalles Bibliográficos
Autores principales: Pachulec, Emilia, Neitzke-Montinelli, Vanessa, Viola, João P. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052263/
https://www.ncbi.nlm.nih.gov/pubmed/27766099
http://dx.doi.org/10.3389/fimmu.2016.00411