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Cause and consequences of the activated type I interferon system in SLE

Patients with systemic lupus erythematosus (SLE) have an increased expression of type I interferon (IFN)-regulated genes (an IFN signature), which is caused by an ongoing production of type I IFNs by plasmacytoid dendritic cells (pDCs). The reasons behind the continuous IFN production in SLE are the...

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Detalles Bibliográficos
Autores principales:	Eloranta, Maija-Leena, Rönnblom, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052287/ https://www.ncbi.nlm.nih.gov/pubmed/27094810 http://dx.doi.org/10.1007/s00109-016-1421-4

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