Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways

ABSTRACT: Keloid disease is characterized by hyperproliferation of responsive fibroblasts with vigorously continuous synthesis of extracellular matrix (ECM) components. Although the process by which keloids develop is poorly understood, most theories of the etiology are referred to fibroblast dysfun...

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Detalles Bibliográficos
Autores principales: Wang, Wenbo, Qu, Miao, Xu, Lan, Wu, Xiaoli, Gao, Zhen, Gu, Tingyu, Zhang, Wenjie, Ding, Xiaoyan, Liu, Wei, Chen, Yue-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052317/
https://www.ncbi.nlm.nih.gov/pubmed/27339758
http://dx.doi.org/10.1007/s00109-016-1430-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052317/
https://www.ncbi.nlm.nih.gov/pubmed/27339758
http://dx.doi.org/10.1007/s00109-016-1430-3

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