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Vasodilator-stimulated phosphoprotein-phosphorylation by ginsenoside Ro inhibits fibrinogen binding to αIIb/β(3) in thrombin-induced human platelets

BACKGROUND: Glycoprotein IIb/IIIa (αIIb/β(3)) is involved in platelet adhesion, and triggers a series of intracellular signaling cascades, leading to platelet shape change, granule secretion, and clot retraction. In this study, we evaluated the effect of ginsenoside Ro (G-Ro) on the binding of fibri...

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Detalles Bibliográficos
Autores principales:	Shin, Jung-Hae, Kwon, Hyuk-Woo, Cho, Hyun-Jeong, Rhee, Man Hee, Park, Hwa-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052406/ https://www.ncbi.nlm.nih.gov/pubmed/27746688 http://dx.doi.org/10.1016/j.jgr.2015.11.003

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