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Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity

The murine epidermis with its hair follicles represents an invaluable model system for tissue regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal how cellular heterogeneity of murine telogen epidermis is tuned at the transcriptional level. Unbiased clustering of 1,...

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Detalles Bibliográficos
Autores principales: Joost, Simon, Zeisel, Amit, Jacob, Tina, Sun, Xiaoyan, La Manno, Gioele, Lönnerberg, Peter, Linnarsson, Sten, Kasper, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052454/
https://www.ncbi.nlm.nih.gov/pubmed/27641957
http://dx.doi.org/10.1016/j.cels.2016.08.010